Pochin E E
At Energy Rev. 1980 Sep;18(3):779-802.
In defining criteria for good protection against ionizing radiation, it is important to assess quantitatively the likely risk of any radiation exposure. The 'somatic' risks to the individual result mainly from induction of cancer in the organs irradiated, and these risks can now be estimated on the basis of numerous detailed epidemiological surveys of exposed human populations. Estimates of the risk of hereditary effects, from genetic changes induced in germ cells, are based largely on the frequency with which such effects are induced in other species. In both cases the risk at very low dose can be inferred using knowledge of the way in which radiation damage is caused in tissues. Coherent systems of radiation protection are based on a restriction of doses to the whole body and to individual organs, such that the induction of cancer and genetic harm is infrequent, and the threshold dose for causing other, 'non-stochastic', effects is not exceeded.
在定义针对电离辐射的良好防护标准时,定量评估任何辐射暴露的可能风险非常重要。对个体的“躯体”风险主要源于受照射器官中癌症的诱发,现在可以根据对受照射人群进行的大量详细流行病学调查来估计这些风险。对生殖细胞中诱导的遗传变化所产生的遗传效应风险的估计,很大程度上基于在其他物种中诱导此类效应的频率。在这两种情况下,都可以利用对组织中辐射损伤产生方式的了解来推断极低剂量下的风险。连贯的辐射防护体系基于对全身和各个器官剂量的限制,以使癌症和遗传损害的诱发很少发生,并且不超过导致其他“非随机”效应的阈值剂量。