Bossa R, Galatulas I, Perrone G
Chemotherapy. 1981;27(5):350-3. doi: 10.1159/000238003.
Gentamicin and adriamycin were tested against eight strains of Proteus mirabilis: using the cellophane transfer technique, combinations of these antibiotics were screened for bactericidal activity. On mice bearing Ehrlich ascites carcinoma, the antitumoral effect of a combination of gentamicin and adriamycin was determined. Antagonism occurred with the combination in bactericidal activity and not in antitumoral activity.
对庆大霉素和阿霉素针对8株奇异变形杆菌进行了测试:采用玻璃纸转移技术,对这些抗生素的组合进行杀菌活性筛选。在患有艾氏腹水癌的小鼠身上,测定了庆大霉素和阿霉素组合的抗肿瘤效果。该组合在杀菌活性方面出现拮抗作用,但在抗肿瘤活性方面未出现。