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伴有真皮-表皮交界处线性IgG和C3沉积的扁平苔藓(作者译)

[Lichen planus with linear IgG and C3 deposits at the dermal-epidermal junction (author's transl)].

作者信息

Morel P, Perron J, Crickx B, Barrandon Y, Civatte J

出版信息

Dermatologica. 1981;163(1):117-24.

PMID:7024005
Abstract

Report of 4 cases of clinically and histologically typical lichen planus with a linear IgG and C3 deposit at the dermal-epidermal junction in involved (4/4) and healthy (2/2) skin, as detected by direct immunofluorescence. Indirect immunofluorescence was negative (3/3). In these 4 cases, the clinical aspect was different: there were no vesiculo-bullous lesions in case 1; case 2 and 3 were of the partly vesicular type with dermal-epidermal separation only in the involved skin; in case 4, bullae were present on both healthy and lesional skin. This suggests that there might exist a broad spectrum ranging from lichen planus without clinical vesiculo-bullous lesions, but with linear IgG and C3 deposits, to lichen planus associated with clinical, histological and immunological symptoms of bullous pemphigoid.

摘要

4例临床和组织学表现典型的扁平苔藓报告,通过直接免疫荧光检测发现,在受累皮肤(4/4)和健康皮肤(2/2)的真皮 - 表皮交界处有线性IgG和C3沉积。间接免疫荧光为阴性(3/3)。在这4例中,临床情况有所不同:病例1无水疱 - 大疱性损害;病例2和3为部分水疱型,仅在受累皮肤有真皮 - 表皮分离;病例4在健康皮肤和病变皮肤均有大疱。这表明可能存在一个广泛的谱系,从无临床水疱 - 大疱性损害但有线性IgG和C3沉积的扁平苔藓,到伴有大疱性类天疱疮临床、组织学和免疫学症状的扁平苔藓。

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