Campo E, Bombi J A
Virchows Arch A Pathol Anat Histol. 1981;391(1):117-22. doi: 10.1007/BF00589799.
Heterotopic glial tissue was seen within the lungs of a newborn with a cranial malformation and anterior spina bifida. Histological examination of the lung showed solid islands of glial tissue intermingled with pulmonary structures. Well developed bronchioles that were in continuity with the main bronchial tree could be identified within the nodules. The central cystic cavity of the nodules is a bronchial lumen probably dilated by the respiratory movements. Several hypotheses have been elaborated to explain the heterotopic glial tissue in lung. The presence of an anterior spina bifida suggests a migratory mechanism to explain the embryogenesis of this case.
在一名患有颅骨畸形和脊柱裂的新生儿肺部发现了异位神经胶质组织。对肺部进行组织学检查显示,神经胶质组织的实性岛状结构与肺部结构交织在一起。在结节内可以识别出与主支气管树相连的发育良好的细支气管。结节的中央囊腔是一个可能因呼吸运动而扩张的支气管腔。已经提出了几种假说来解释肺部异位神经胶质组织的存在。脊柱裂的存在提示了一种迁移机制来解释该病例的胚胎发生。