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氟比洛芬与眼压

Flurbiprofen and intraocular pressure.

作者信息

Gieser D K, Hodapp E, Goldberg I, Kass M A, Becker B

出版信息

Ann Ophthalmol. 1981 Jul;13(7):831-3.

PMID:7027872
Abstract

Systemic or topical administration of corticosteroids may produce a rise in intraocular pressure (IOP). Nonsteroidal anti-inflammatory drugs (NSAI drugs) are alternate therapy for ocular inflammatory disease. Flurbiprofen, a new NSAI drug, was tested in double-masked fashion to delineate its effect on IOP. Flurbiprofen did not alter IOP in known high corticosteroid responders nor did it block corticosteroid-induced ocular hypertension.

摘要

全身或局部使用皮质类固醇可能会导致眼压升高。非甾体抗炎药(NSAI药物)是眼部炎症性疾病的替代疗法。新型NSAI药物氟比洛芬以双盲方式进行测试,以确定其对眼压的影响。氟比洛芬在已知对皮质类固醇反应强烈的患者中不会改变眼压,也不会阻止皮质类固醇诱发的高眼压。

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Ann Ophthalmol. 1981 Jul;13(7):831-3.
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引用本文的文献

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Corticosteroids in ophthalmology: drug delivery innovations, pharmacology, clinical applications, and future perspectives.眼科中的皮质类固醇:药物输送创新、药理学、临床应用和未来展望。
Drug Deliv Transl Res. 2021 Jun;11(3):866-893. doi: 10.1007/s13346-020-00843-z.
2
Steroid-induced Glaucoma: An Avoidable Irreversible Blindness.类固醇性青光眼:一种可避免的不可逆性失明。
J Curr Glaucoma Pract. 2017 May-Aug;11(2):67-72. doi: 10.5005/jp-journals-l0028-1226. Epub 2017 Aug 5.
3
Corticosteroids and glaucoma risk.皮质类固醇与青光眼风险。
Drugs Aging. 1999 Dec;15(6):439-50. doi: 10.2165/00002512-199915060-00004.
4
The emerging roles of topical non-steroidal anti-inflammatory agents in ophthalmology.局部用非甾体抗炎药在眼科领域的新作用
Br J Ophthalmol. 1996 May;80(5):480-5. doi: 10.1136/bjo.80.5.480.
5
Laser induced thermal injury of rabbit cornea and treatment with anti-inflammatory agents.激光诱导兔角膜热损伤及抗炎药物治疗
Doc Ophthalmol. 1985 Apr 30;59(3):277-99. doi: 10.1007/BF00159265.
6
An evaluation of the anti-inflammatory effect of flurbiprofen after cataract extraction.氟比洛芬在白内障摘除术后的抗炎作用评估。
Br J Ophthalmol. 1987 Jun;71(6):418-21. doi: 10.1136/bjo.71.6.418.