Phulke Sonia, Kaushik Sushmita, Kaur Savleen, Pandav S S
Senior Resident, Department of Ophthalmology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Professor, Advanced Eye Centre, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
J Curr Glaucoma Pract. 2017 May-Aug;11(2):67-72. doi: 10.5005/jp-journals-l0028-1226. Epub 2017 Aug 5.
Steroids are a group of anti-inflammatory drugs, commonly used to treat ocular and systemic conditions. Unmonitored use of steroids especially in eye drop formulations is common in situations when it is easily available over-the-counter, resulting in undesirable side effects. Among the ocular side effects, cataract and glaucoma are common. Steroid-induced ocular hypertension was reported in 1950, when long-term use of systemic steroid was shown to increase the intraocular pressure (IOP). Chronic administration of steroids in any form with raised IOP can cause optic neuropathy resulting in steroid-induced glaucoma. This review describes the pathophysiology and epidemiology of steroid-induced glaucoma, recognition of side effects, and principles of management. The purpose is to familiarize all clinicians with the potential dangers of administering steroids without monitoring the eye and the dangers of irreversible blind -ness in some instances of habitual self-prescription by patients.
Phulke S, Kaushik S, Kaur S, Pandav SS. Steroid-induced Glaucoma: An Avoidable Irreversible Blindness. J Curr Glaucoma Pract 2017;11(2):67-72.
类固醇是一类抗炎药物，常用于治疗眼部和全身性疾病。在非处方即可轻易获得类固醇的情况下，尤其是眼药水剂型，无监测使用类固醇的情况很常见，这会导致不良副作用。在眼部副作用中，白内障和青光眼较为常见。1950年报道了类固醇诱导的眼压升高，当时显示长期使用全身性类固醇会升高眼压（IOP）。以任何形式长期使用类固醇且眼压升高会导致视神经病变，进而引发类固醇性青光眼。本综述描述了类固醇性青光眼的病理生理学和流行病学、副作用的识别以及治疗原则。目的是让所有临床医生熟悉在不监测眼睛的情况下使用类固醇的潜在危险，以及患者习惯性自我用药某些情况下不可逆转失明的危险。
Phulke S, Kaushik S, Kaur S, Pandav SS。类固醇性青光眼：一种可避免的不可逆失明。《当代青光眼实践杂志》2017年；11(2):67 - 72。
