[Effect of thermal stress on the morphogenetic potencies of nephron epithelium].

Experiments on 46 male rats aged 6 months have been carried out to study the effect of thermal stress on biological potencies of the nephron epithelium with the use of the F. M. Lazarenko's method for cultivating organs and tissues in the body. Acute hyperthermia was found to intensify the destruction of proximal parts and renal corpuscles, to activate and prolong the proliferative phase of the implantation growth. In the implants, the epithelium gives rise to the formation of lining layers, immersion growth bands and spongy structures. In the course of differentiation there form atypical renal corpuscles and epithelial tubules whose structure conforms to the proximal and distal parts, as well as to Henle's loop. Thermal stress initiates morphogenetic potencies of the nephron epithelium. The method of cultivation under consideration holds promise for elaborating objective criteria of the appraisal of the effect produced by extreme factors on biological properties of tissues.