Ianishevskaia M N
Zh Mikrobiol Epidemiol Immunobiol. 1981 Sep(9):38-41.
The exotoxins of Shigella dysenteriae, serovars 3-7, were isolated. These exotoxins were found to differ from O-antigens in their chemical composition and resistance to heating, drying and the action of chemical substances. The toxicity of exotoxin was determined by its thermolabile component. Exotoxin formation varied in different strains. The preparations obtained from the cultures in the S-form, isolated from patients with severe toxic forms of the infectious process, possessed the highest toxicity. The cultures (in the S- and R-forms), kept for a long time in culture media at the museum of the laboratory, completely lost their capacity for exotoxin synthesis.
分离出了痢疾志贺氏菌3 - 7血清型的外毒素。发现这些外毒素在化学组成以及对加热、干燥和化学物质作用的抗性方面与O抗原不同。外毒素的毒性由其热不稳定成分决定。不同菌株中外毒素的形成情况各异。从患有严重感染中毒型疾病患者身上分离得到的S型培养物所制备的制剂毒性最高。在实验室博物馆的培养基中长期保存的培养物（S型和R型）完全丧失了合成外毒素的能力。
