O'Rahilly R, Bossy J, Müller F
Bull Assoc Anat (Nancy). 1981 Jun;65(189):141-236.
The internationally accepted Carnegie system of 23 developmental stages for the embryonic period proper (the first 8 post-ovulatory weeks) is outlined. At the end of this period the human embryo measures about 30 mm in C.-R. length. Some common misusages are noted, e.g., arabic numerals should be used for the states and the term "horizon" is obsolete; embryonic length is not a stage; STREETER's ages were based on the macaque and do not apply to the human. The introduction includes a discussion of the Carnegie Embryological Collection, the embryonic period, developmental stages, and finally a guide to embryonic staging in the human. An atlas of photographs of external views of embryos at the various Carnegie states is provided. Stages 1 to 8 (the presomite period, up to about 18 days) are described briefly and illustrated with photographs and photomicrographs. Stages 9 to 12 (the somitic period, about 20 to 26 days) and stages 13 to 23 (the postsomitic period, 4 to 8 post-ovulatory weeks) are summarized with reference to both external and internal development, and illustrated with photographs of the external appearances. In addition to (A) certain references cited in the introduction and in the text, the bibliography includes : (B) an annotated list of general works on staged human embryos, (C) an annotated list of selected examples of stages 1 to 15, and (D) an annotated list of references to information concerning staged embryos arranged according to the various systems of the body.
本文概述了国际公认的适用于胚胎期(排卵后最初8周)的23个发育阶段的卡内基系统。在此阶段结束时,人类胚胎的头臀长度约为30毫米。文中指出了一些常见的误用情况,例如,阶段应用阿拉伯数字表示,“horizon”一词已过时;胚胎长度并非一个阶段;斯特里特分期基于猕猴,不适用于人类。引言部分讨论了卡内基胚胎学收藏、胚胎期、发育阶段,最后是人类胚胎分期指南。提供了各卡内基阶段胚胎外观照片图集。简要描述了第1至8阶段(前体节期,直至约18天),并配有照片和显微照片。参照外部和内部发育情况总结了第9至12阶段(体节期,约20至26天)以及第13至23阶段(体节后时期,排卵后4至8周),并配有外观照片。除引言和正文引用的某些参考文献外,参考文献还包括:(B)关于分期人类胚胎的一般著作注释列表,(C)第1至15阶段选定示例的注释列表,以及(D)按身体各系统排列的关于分期胚胎信息的参考文献注释列表。