Davidson A T
J Natl Med Assoc. 1981 Nov;73(11):1089-92.
Cancer of the breast is the leading type of cancer in women in the United States (28 percent), and the leading cause of death from cancer in women (20 percent). More than half of the cases of breast cancer can be anticipated to exhibit recurrent disease. Most deaths occur within five years of discovery. There has been a minimum reduction in the mortality rate in the past 35 years. This failure is due to microemboli that spread via both the lymphatic and vascular systems in the early predetection state of the primary lesion. In Stage I and Stage II disease, modified radical mastectomy is the treatment of choice. In Stage III disease, radical mastectomy gives a higher incidence of local control of the disease without an increased chance of survival. Adjuvant chemotherapy offers a definite improvement in survival rates.
乳腺癌是美国女性中最常见的癌症类型（占28%），也是女性癌症死亡的主要原因（占20%）。超过一半的乳腺癌病例预计会出现疾病复发。大多数死亡发生在发现后的五年内。在过去35年里，死亡率的降低幅度极小。这种情况的出现是由于在原发性病变的早期预检测阶段，微栓子通过淋巴系统和血管系统扩散。对于I期和II期疾病，改良根治性乳房切除术是首选治疗方法。对于III期疾病，根治性乳房切除术在局部控制疾病方面有较高的发生率，但生存率并未提高。辅助化疗确实提高了生存率。
