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[磷酸肌酸钠与心血管和呼吸系统]

[Sodium phosphocreatine and the cardiovascular and respiratory systems].

作者信息

Lampa E, Perna D, Giasi M, Imperatore A, Visone C, Somma A, Ottavo R, Matera G, Ruggiero E, Pierri T, Marmo E

出版信息

Arch Sci Med (Torino). 1981 Jul-Sep;138(3):365-98.

PMID:7032463
Abstract

In the dog, rat and chick, phosphocreatine-Na has not caused, from an experimental point of view, significative modifications of the cardiovascular- and respiratory-apparatus, of the reactivity of the cardio-regulator centers, of the baroreceptorial carotid-sinus and glomus reactivity, of the gangliar-, muscarinic-, histaminergic-, dopaminergic-, beta-adrenergic- and serotoninergic- vasomotor reactivity; only the vasomotor reactivity of a constrictive-type induced by epinephrine, nor-epinephrine, occlusion of the two common carotid arteries, hypertension and by BaCl2 is moderately reduced. It is interesting to note that the hypotensive response evoked by adenosine was augmented.

摘要

在犬、大鼠和鸡身上,从实验角度来看,磷酸肌酸 - 钠并未引起心血管和呼吸系统、心脏调节中枢反应性、压力感受器颈动脉窦和球旁器反应性、神经节、毒蕈碱、组胺能、多巴胺能、β - 肾上腺素能和5 - 羟色胺能血管运动反应性的显著改变;仅由肾上腺素、去甲肾上腺素、双侧颈总动脉闭塞、高血压和氯化钡诱导的收缩型血管运动反应性略有降低。值得注意的是,腺苷诱发的降压反应增强了。

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