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链球菌细胞壁肽聚糖 - 多糖聚合物诱导的补体体内变化。

In vivo changes in complement induced with peptidoglycan-polysaccharide polymers from streptococcal cell walls.

作者信息

Lambris J D, Allen J B, Schwab J H

出版信息

Infect Immun. 1982 Jan;35(1):377-80. doi: 10.1128/iai.35.1.377-380.1982.

Abstract

In rats injected with an arthropathogenic dose of streptococcal cell wall fragments, serum hemolytic activity decreased over the first 24 h and was then elevated from days 2 through 6 after injection. Hemolytic activity was again elevated at days 16 and 40. Levels of activity of alternative complement pathway, C3, and factor D were also altered.

摘要

给大鼠注射致关节炎剂量的链球菌细胞壁碎片后,血清溶血活性在最初24小时内降低,然后在注射后第2天至第6天升高。溶血活性在第16天和第40天再次升高。替代补体途径、C3和因子D的活性水平也发生了改变。

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Soluble peptidoglycan-polysaccharide fragments of the bacterial cell wall induce acute inflammation.
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