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胃成形术和胃底折叠术在复杂反流问题管理中的应用

Gastroplasty and fundoplication in the management of complex reflux problems.

作者信息

Pearson F G, Cooer J D, Nelems J M

出版信息

J Thorac Cardiovasc Surg. 1978 Nov;76(5):665-72.

PMID:703371
Abstract

Between 1963 and 1976, 220 patients with complex reflux problems were managed by combining a modified Collis gastroplasty with a Belsey type of partial fundoplication. All patients had one or more of the following complicating conditions considered indications for the combined operation: peptic stricture (104), esophagitis and shortening without stricture (25), one or more prior hiatal repairs (65), massive herniation (33), and motor disorders associated with reflux (26). Ninety-six percent of the patients were evaluated by personal interview from 1 to 15 years after repair. The operative mortality rate was 0.5 percent. The incidence of significant symptomatic reflux requiring medical therapy was 3 percent and the incidence of troublesome dysphagia was 11 percent. No patient has required further operation for the relief of recurrent symptomatic reflux. Two patients required additional operation for severe residual dysphagia. Twenty patients managed by this repair were evaluated by preoperative, intraoperative, and sequential postoperative esophageal pressure studies. The mean postoperative pressure of 21.4 mm. Hg was more than double the preoperative value. Two publications from other centers reported on similar groups of patients managed by gastroplasty and partial fundoplication, evaluated by preoperative and postoperative esophageal pressures. In these latter publications, the percentage increase in postoperative lower esophageal pressure was significantly less than in our study, and a much higher incidence of symptomatic reflux was recorded. We suggest that the differences in postoperative pressures observed in account for the pronounced differences in the quality of results obtained.

摘要

1963年至1976年间,220例患有复杂反流问题的患者接受了改良的科利斯胃成形术与贝尔西式部分胃底折叠术相结合的治疗。所有患者都有以下一种或多种被视为联合手术指征的复杂情况:消化性狭窄(104例)、无狭窄的食管炎和食管缩短(25例)、一次或多次先前的裂孔修补术(65例)、巨大疝(33例)以及与反流相关的运动障碍(26例)。96%的患者在修复术后1至15年接受了个人访谈评估。手术死亡率为0.5%。需要药物治疗的明显症状性反流发生率为3%,令人烦恼的吞咽困难发生率为11%。没有患者因复发性症状性反流而需要进一步手术。两名患者因严重的残余吞咽困难而需要再次手术。对通过这种修复治疗的20例患者进行了术前、术中和术后连续食管压力研究评估。术后平均压力为21.4毫米汞柱,是术前值的两倍多。其他中心的两篇出版物报道了通过胃成形术和部分胃底折叠术治疗的类似患者群体,并通过术前和术后食管压力进行了评估。在这些后来的出版物中,术后食管下段压力的增加百分比明显低于我们的研究,并且记录到的症状性反流发生率要高得多。我们认为观察到的术后压力差异解释了所获得结果质量的显著差异。

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