Kubik M M, Coote J H
Postgrad Med J. 1981;57 Suppl 2:44-50.
The effects on blood pressure and heart rate of 200 mg metoprolol and 2.5 mg indapamide given separately and together as a single daily dose were compared in 27 patients suffering from moderate hypertension. The blood pressure and heart rate were measured in the lying and standing position, before, during and after exercise. Both indapamide and metoprolol in a single daily dose reduced the blood pressure. The best results were achieved by a combination of the two.
对27例中度高血压患者比较了每日单剂量分别给予200毫克美托洛尔和2.5毫克吲达帕胺以及二者合用时对血压和心率的影响。在运动前、运动期间和运动后，测量卧位和立位的血压及心率。吲达帕胺和每日单剂量美托洛尔均能降低血压。二者联用效果最佳。
