Gyr T, Hedinger C
Schweiz Med Wochenschr. 1981 Nov 28;111(48):1839-45.
In a retrospective study of their autopsy cases the authors investigate the presence of lymphocytic infiltrations in the thyroids of 44 diabetics up to age 55 and compare these thyroids with 72 post-mortem controls. Size and number of the infiltrations were determined by a semiquantitative method on the histological slide. The non-diabetic controls and the non-insulin-dependent diabetics included 5 out of 72 (6.9%) and 3 out of 31 (9.7%) cases respectively with more than 10 infiltrations per 100 mm2 thyroid tissue. The insulin-dependent diabetics, however, showed significantly more, i.e. 5 out of 13 (38.5%) patients with more than 10 infiltrations per 100 mm2 tissue. All were asymptomatic with the exception of one young diabetic with clinical signs of hypothyroidism.
在一项对尸检病例的回顾性研究中,作者调查了44名年龄在55岁以下的糖尿病患者甲状腺中淋巴细胞浸润的情况,并将这些甲状腺与72例死后对照进行比较。通过对组织学切片采用半定量方法确定浸润的大小和数量。非糖尿病对照组和非胰岛素依赖型糖尿病组中,每100平方毫米甲状腺组织浸润超过10个的病例分别占72例中的5例(6.9%)和31例中的3例(9.7%)。然而,胰岛素依赖型糖尿病患者中,每100平方毫米组织浸润超过10个的患者比例显著更高,即13例中有5例(38.5%)。除了一名有甲状腺功能减退临床症状的年轻糖尿病患者外,其他患者均无症状。