Ristic M, Huxsoll D L, Tachibana N, Rapmund G
Am J Trop Med Hyg. 1981 Nov;30(6):1324-8. doi: 10.4269/ajtmh.1981.30.1324.
A serologic relationship between Rickettsia sennetsu, the etiologic agent of human sennetsu rickettsiosis in western Japan, and Ehrlichia canis, the agent of canine ehrlichiosis, has been demonstrated. Using the indirect fluorescent antibody test, convalescent sera from patients with sennetsu fever reacted with Ehrlichia canis antigen. In the direct fluorescent antibody test, immunoglobulins from four patients with sennetsu rickettsiosis stained E. canis morulae in canine monocytes. This finding is significant in view of the morphologic uniqueness of the two agents and a lack of serologic relatedness with other major rickettsial agents.
已证实，日本西部人类森内次立克次体病的病原体——森内次立克次体与犬埃立克体病的病原体——犬埃立克体之间存在血清学关系。采用间接荧光抗体试验，森内次热患者的恢复期血清与犬埃立克体抗原发生反应。在直接荧光抗体试验中，4例森内次立克次体病患者的免疫球蛋白使犬单核细胞内的犬埃立克体桑葚体着色。鉴于这两种病原体形态学上的独特性以及与其他主要立克次体病原体缺乏血清学相关性，这一发现具有重要意义。
