甲砜霉素治疗男性软下疳
Thiamphenicol in the treatment of chancroid in men.
作者信息
Latif A S
出版信息
Br J Vener Dis. 1982 Feb;58(1):54-5. doi: 10.1136/sti.58.1.54.
Abstract
Thiamphenicol was used to treat 547 men with chancroid. An oral dose of 2.5g was given on the first day and a further dose of 1.25g a week later if the lesions had not healed. Eighty-seven (15.9%) patients defaulted from follow up and 23 (4.2%) had positive serological test results for syphilis. Of the remaining 437 patients, 27 (6.2%) failed to respond to treatment, 258 (59%) were cured after the single dose, and 152 (34.8%) required a second dose. The overall cure rate was 93.8%.
摘要
甲砜霉素用于治疗547例软下疳男性患者。首日口服剂量为2.5g，若病灶未愈合，则在一周后再给予1.25g剂量。87例（15.9%）患者失访，23例（4.2%）梅毒血清学检测结果呈阳性。在其余437例患者中，27例（6.2%）治疗无效，258例（59%）单剂量治疗后治愈，152例（34.8%）需要第二剂治疗。总治愈率为93.8%。
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