de Vitry F, Picart R, Jacque C, Tixier-Vidal A
Dev Neurosci. 1981;4(6):457-60. doi: 10.1159/000112813.
The differentiation of tanycytes during development of the mouse hypothalamus has been followed by immunohistochemistry with a GFA protein antiserum. Radially oriented processes of the tanycytes were stained with GFA antiserum in the ventral and the dorsal lining of the third ventricle in the mouse neonate and at later ages. Typical astrocytes in the hypothalamus could not be visualized before 16-20 days postnatally. These results indicate that tanycytes, which acquire their final position early in embryonic development, exhibit a structural feature of fully differentiated astrocytes early in postnatal development.
在小鼠下丘脑发育过程中，运用胶质纤维酸性蛋白（GFA）抗血清通过免疫组织化学方法追踪了伸展细胞的分化过程。在新生小鼠及稍大些的小鼠中，第三脑室腹侧和背侧衬里的伸展细胞呈放射状排列的突起被GFA抗抗蛋白抗血清染上色。下丘脑典型的星形胶质细胞在出生后16 - 20天之前无法显现。这些结果表明，伸展细胞在胚胎发育早期就获得了其最终位置，在出生后发育早期就展现出完全分化的星形胶质细胞的结构特征。
