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[内科疾病中的碳水化合物输注。代谢健康、肝病和糖尿病患者的比较研究。VI. 48小时内输注葡萄糖/木糖醇混合物(1:1比例)]

[Carbohydrate infusion in internal diseases. A comparative study in metabolically healthy, liver diseased and diabetic patients. VI. Infusions of a glucose/xylitol mixture (1:1 ratio) over a 48-hour period].

作者信息

Egberts E H, Rittershofer H, Müller P H, Schmülling R, Prestele H, Horbach L, Malchow H

出版信息

Infusionsther Klin Ernahr. 1982 Apr;9(2):92-6.

PMID:7044970
Abstract

By central venous catheterization, 6 control persons, 7 patients with liver cirrhosis and 6 patients with diabetes mellitus were infused for 48 h with a 20% (w/v) mixture of glucose/xylitol (1:1). The infusion 48 h with a 20% (w/v) mixture of glucose/xylitol (1:1). The infusion rate of 0.125 g monosaccharide/kg/h could be maintained with minor deviations. There were no significant changes in blood glucose levels using this infusion regimen. Lactate levels, however, did increase constantly during the whole infusion period. In the liver group as well as in the diabetic group we could measure values between 1.5 and 3.9 mmol/l. Triglycerides increased solely in the diabetic group. Uric acid concentrations were elevated in all 3 groups. Clinically significant side effects were not observed.

摘要

通过中心静脉置管,对6名对照者、7名肝硬化患者和6名糖尿病患者输注20%(重量/体积)葡萄糖/木糖醇(1:1)混合液48小时。以0.125克单糖/千克/小时的输注速率进行输注,偏差较小。采用该输注方案时,血糖水平无显著变化。然而,在整个输注期间,乳酸水平持续升高。在肝脏组和糖尿病组中,我们测得的值在1.5至3.9毫摩尔/升之间。甘油三酯仅在糖尿病组中升高。三组患者的尿酸浓度均升高。未观察到具有临床意义的副作用。

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