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[内科疾病中的碳水化合物输注。对代谢正常受试者、肝病患者和糖尿病患者的比较研究。V. 输注葡萄糖 - 山梨醇混合物(比例1:1)48小时]

[Carbohydrate infusions in internal diseases. A comparative study in metabolically normal subjects, patients with liver diseases and diabetics. V. Infusion of a glucose-sorbitol mixture (ratio 1:1) for 48 hours].

作者信息

Müller P H, Egberts E H, Beerenfeld A, Schmülling R, Prestele H, Horbach L, Malchow H

出版信息

Infusionsther Klin Ernahr. 1982 Feb;9(1):16-9.

PMID:7076289
Abstract

Three groups (6 patients with liver cirrhosis, 6 patients with diabetes mellitus, 6 controls) have been infused for 48 h with a 20% (w/v) glucose/sorbitol-solution (1:1). The only group where the infusion rate of 0,25 g carbohydrates/kg/h could not be reached was the control group with 0,232 g carbohydrates/kg/h. We could not see any significant changes in blood glucose levels during the total infusion period. Sorbitol levels dropped very slowly after the end of the infusion, a time when sorbitol was still excreted in the urine. The concentration of triglycerides was steadily increasing. Besides there were no further changes compared to equicaloric glucose or glucose/fructose infusions.

摘要

三组(6例肝硬化患者、6例糖尿病患者、6例对照组)接受20%(w/v)葡萄糖/山梨醇溶液(1:1)输注48小时。唯一未达到0.25克碳水化合物/千克/小时输注速率的组是对照组,其输注速率为0.232克碳水化合物/千克/小时。在整个输注期间,我们未观察到血糖水平有任何显著变化。输注结束后,山梨醇水平下降非常缓慢,此时山梨醇仍在尿液中排泄。甘油三酯浓度稳步上升。此外,与等热量葡萄糖或葡萄糖/果糖输注相比,没有进一步变化。

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