Lowe D, Jorizzo J, Hutt M S
J Clin Pathol. 1981 Dec;34(12):1343-8. doi: 10.1136/jcp.34.12.1343.
In a recent study of cervical carcinoma, 13 cases with a marked eosinophil infiltrate around the tumour were found. The histological appearance of the tumours was distinctive and suggested a specific response, similar to the lymphocyte infiltration in medullary carcinoma of the breast and seminoma. A review of published reports shows that tumour-associated tissue eosinophilia (TATE) and tumour-associated blood eosinophilia (TABE) may be seen in tumours of different histological types from different anatomical sites, and may occur together or separately. Tumours with TATE alone appear to have a better prognosis that those without, while TABE is associated with tumor spread and a poor prognosis.
在最近一项关于宫颈癌的研究中,发现13例肿瘤周围有明显嗜酸性粒细胞浸润。肿瘤的组织学表现独特,提示一种特定反应,类似于乳腺髓样癌和精原细胞瘤中的淋巴细胞浸润。对已发表报告的回顾显示,肿瘤相关组织嗜酸性粒细胞增多症(TATE)和肿瘤相关血液嗜酸性粒细胞增多症(TABE)可见于来自不同解剖部位的不同组织学类型的肿瘤,且可能同时或分别出现。仅伴有TATE的肿瘤似乎比无TATE的肿瘤预后更好,而TABE与肿瘤扩散及预后不良相关。