Littlejohn G O, Smythe H A
J Rheumatol. 1981 Nov-Dec;8(6):965-8.
The insulin response after a glucose challenge was studied in 11 male patients with diffuse idiopathic skeletal hyperostosis (DISH) and in 8 age, sex and weight matched controls. There was significant hyperinsulinemia in the DISH group, most marked at 2 h after the glucose challenge. Growth hormone levels were found to be normal in each group. The marked hyperinsulinemia in patients with DISH may play a role in the pathogenesis of this condition.
对11名患有弥漫性特发性骨肥厚（DISH）的男性患者以及8名年龄、性别和体重相匹配的对照者进行了葡萄糖耐量试验后的胰岛素反应研究。DISH组存在明显的高胰岛素血症，在葡萄糖耐量试验后2小时最为显著。发现每组的生长激素水平均正常。DISH患者中明显的高胰岛素血症可能在该疾病的发病机制中起作用。
