Cannon J G, Long J P, Bhatnagar R
J Med Chem. 1981 Oct;24(10):1113-8. doi: 10.1021/jm00142a001.
The physiological and pharmacological roles of pre- and postsynaptic dopamine receptors in modification of neuronal transmission centrally and peripherally will be subjects for intense research during the next decade. As enumerated by Langer, dopamine-sensitive receptors have been described that may inhibit or facilitate release of neurotransmitter substances. It is likely that dopaminergic agents that are highly selective for specific transmitters will be discovered. Likewise, dopaminergic agents that are nonselective (i.e., that modify the function of two or more neurotransmitters) may offer many opportunities for modification of behavior.
突触前和突触后多巴胺受体在中枢和外周神经传递调节中的生理和药理作用将是未来十年深入研究的课题。正如兰格所列举的，已经描述了对多巴胺敏感的受体，它们可能抑制或促进神经递质的释放。很可能会发现对特定递质具有高度选择性的多巴胺能药物。同样，非选择性的多巴胺能药物（即改变两种或更多种神经递质功能的药物）可能为行为调节提供许多机会。
