Macdonald J S, Haller D G, Kisner D L
Recent Results Cancer Res. 1982;80:284-90. doi: 10.1007/978-3-642-81685-7_45.
The adjuvant chemotherapy of colorectal and gastric cancer is being actively investigated. Studies of both single antineoplastic agents and combinations of several drugs have been used. In colorectal cancer, single-agent therapy has not resulted in improved survival. Combination chemotherapy studies are at too early a stage to be evaluated. In gastric cancer, single-agent chemotherapy has not been effective as adjunctive treatment to surgery. Combinations of active agents in gastric cancer hold promise as effective surgical adjuvant therapy.
结直肠癌和胃癌的辅助化疗正在积极研究中。已对单一抗肿瘤药物及几种药物联合使用进行了研究。在结直肠癌中,单药治疗未提高生存率。联合化疗研究尚处于早期阶段,无法评估。在胃癌中,单药化疗作为手术辅助治疗并不有效。胃癌中活性药物联合使用有望成为有效的手术辅助治疗方法。