Dyer P A, Klouda P T, Johnson R W, Read A P, Mallick N P, Harris R
Transplantation. 1981 Nov;32(5):424-5. doi: 10.1097/00007890-198111000-00017.
Forty-five donor and recipient primary cadaveric kidney transplant pairs were phenotyped for the properdin factor B (Bf) polymorphism. Graft survival was analyzed on the basis of Bf matching between donor and recipient. Patients receiving a Bf-identical kidney had significantly better graft survival than those receiving a Bf-incompatible kidney (P = 0.045). It is postulated that Bf, which maps in the major histocompatibility system, is a marker for genes of importance in kidney transplant survival.
对45对供体和受体的原发性尸体肾移植进行备解素因子B(Bf)多态性表型分析。根据供体和受体之间的Bf匹配情况分析移植物存活率。接受Bf相同肾脏的患者移植物存活率明显高于接受Bf不匹配肾脏的患者(P = 0.045)。据推测,位于主要组织相容性系统中的Bf是肾移植存活中重要基因的一个标志物。