Mocellin R
Herz. 1982 Feb;7(1):42-9.
In children with congenital heart disease ergometry may be used to measure cardiovascular performance capacity as well as to obtain detailed studies of the functional capacity of different aspects of the cardiovascular system by measuring various parameters during exercise and, thus, rendering a more complete preoperative or postoperative evaluation and possibly contributing to establishment of an indication for surgery. The direct method for measuring cardiovascular performance capacity is the determination of aerobic capacity. All indirect methods such as the W170 (the physical working capacity at a heart rate of 170 beats/min) permit only a rough estimation of working capacity. Since reliable normal values for aerobic capacity of representative samples of boys and girls in different age groups have not been rigidly established, plausible standard values have been estimated in relation to sex, age and body height from previously published data. Subsequently, maximal values for cardiac output have been calculated for all age groups based on a maximal arteriovenous oxygen difference of 13.5 ml/100 ml and, based on a mean maximal heart rate of 200 beats/min, the respective values for stroke volume during exercise have been calculated. In consideration of the fact that equal percentages of aerobic capacity correspond to equal values of arteriovenous oxygen difference, relationships between oxygen uptake and cardiac output were derived for boys and girls of different age groups. The respective regression lines run parallel to a regression valid for male adults which was derived from the values of Ekblom et al. [7] and is based on the formula Q[l/min] = 5.1 + 5.8 VO2[l/min]. In order to permit comparison independent of sex and age, the cardiac output values at rest and during exercise were corrected by subtracting the respective age-related intercepts. The resulting regression line representing normal values independent of sex and age has the formula: Qcorr[l/min] = 5.8 VO2[l/min]. Of particular clinical relevance in these young patients is that the question of feasibility of participation in school physical education classes can generally be answered. Children with congenital heart disease incurring severe hemodynamic compromise have frequently undergone corrective surgery in the pre-school age and the functional results can be assessed accordingly; in children with cyanotic heart disease in whom either no surgery or only a palliative procedure has been performed, ergometry may document severe hemodynamic derangement in spite of a seemingly bland history.
对于患有先天性心脏病的儿童,运动试验可用于测量心血管功能容量,还可通过在运动期间测量各种参数,对心血管系统不同方面的功能能力进行详细研究,从而进行更全面的术前或术后评估,并可能有助于确定手术指征。测量心血管功能容量的直接方法是测定有氧能力。所有间接方法,如W170(心率为170次/分钟时的体力工作能力),只能对工作能力进行粗略估计。由于尚未严格确定不同年龄组男孩和女孩代表性样本的可靠有氧能力正常值,因此根据先前发表的数据,按性别、年龄和身高估算了合理的标准值。随后,基于13.5 ml/100 ml的最大动静脉氧差,计算了所有年龄组的心输出量最大值,并基于平均最大心率200次/分钟,计算了运动期间的相应每搏输出量值。考虑到有氧能力的相同百分比对应于相同的动静脉氧差值这一事实,得出了不同年龄组男孩和女孩的摄氧量与心输出量之间的关系。各自的回归线与男性成年人有效的回归线平行,该回归线由埃克布洛姆等人[7]的值推导得出,基于公式Q[升/分钟]=5.1+5.8VO2[升/分钟]。为了实现不受性别和年龄影响的比较,通过减去各自与年龄相关的截距来校正静息和运动期间的心输出量值。所得代表不受性别和年龄影响的正常值的回归线公式为:Qcorr[升/分钟]=5.8VO2[升/分钟]。在这些年轻患者中,特别具有临床相关性的是,通常可以回答参与学校体育课是否可行的问题。患有严重血流动力学损害的先天性心脏病儿童常在学龄前接受矫正手术,其功能结果可据此进行评估;对于未进行手术或仅进行姑息性手术的青紫型心脏病儿童,运动试验可能显示尽管病史看似平淡,但存在严重的血流动力学紊乱。