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Luteinizing hormone-releasing factor increases release of human chorionic gonadotrophin in isolated cell columns of normal and malignant trophoblasts.

作者信息

Bützow R

出版信息

Int J Cancer. 1982 Jan 15;29(1):9-11. doi: 10.1002/ijc.2910290103.

DOI:10.1002/ijc.2910290103
PMID:7037656
Abstract

The effect of synthetic luteinizing hormone-releasing factor (LRF) on release of human chorionic gonadotrophin (hCG) was studied by isolated cell columns of normal syncytiotrophoblasts and choriocarcinoma (BeWo) cells. After LRF stimulation the release of hCG by the normal trophoblasts increased up to 4-fold and release by the malignant trophoblasts increased up to 6-fold, indicating a specific effect of LRF on normal and malignant trophoblast cells.

摘要

相似文献

1
Luteinizing hormone-releasing factor increases release of human chorionic gonadotrophin in isolated cell columns of normal and malignant trophoblasts.
Int J Cancer. 1982 Jan 15;29(1):9-11. doi: 10.1002/ijc.2910290103.
2
Response of human chorionic gonadotrophin to luteinizing hormone-releasing hormone stimulation in the culture media of normal human placenta, choriocarcinoma cell lines, and in the serum of patients with gestational trophoblastic disease.人绒毛膜促性腺激素在正常人胎盘、绒毛膜癌细胞系培养基以及妊娠滋养细胞疾病患者血清中对促黄体生成素释放激素刺激的反应。
Placenta. 1987 May-Jun;8(3):257-64. doi: 10.1016/0143-4004(87)90049-x.
3
Spontaneous and gonadotropin-releasing hormone induced human chorionic gonadotropin release from superfused JAR choriocarcinoma cells.自发和促性腺激素释放激素诱导人绒毛膜促性腺激素从经超灌流的JAR绒毛膜癌细胞中释放。
Arch Gynecol Obstet. 1993;253(1):43-9. doi: 10.1007/BF02770633.
4
Detection of the free beta subunit of human chorionic gonadotropin (HCG) in cultures of normal and malignant trophoblast cells, pregnancy sera, and sera of patients with choriocarcinoma.在正常和恶性滋养层细胞培养物、妊娠血清及绒毛膜癌患者血清中检测人绒毛膜促性腺激素（HCG）的游离β亚基。
Endocrinology. 1983 Sep;113(3):1176-8. doi: 10.1210/endo-113-3-1176.
5
Presence of alpha 2-macroglobulin in normal but not in malignant human syncytiotrophoblasts.α2-巨球蛋白存在于正常的人合体滋养层细胞中，而不存在于恶性的人合体滋养层细胞中。
Cancer Res. 1981 Jun;41(6):2507-13.
6
In vitro effect of antiphospholipid antibody-containing sera on basal and gonadotrophin releasing hormone-dependent human chorionic gonadotrophin release by cultured trophoblast cells.含抗磷脂抗体血清对培养的滋养层细胞基础及促性腺激素释放激素依赖性人绒毛膜促性腺激素释放的体外作用。
Placenta. 1995 Jan;16(1):75-83. doi: 10.1016/0143-4004(95)90083-7.
7
Immunohistochemical demonstration of luteinizing hormone-releasing factor-like material in human syncytiotrophoblast and trophoblastic tumours.人合体滋养层细胞和滋养层肿瘤中促黄体生成激素释放因子样物质的免疫组织化学显示
Clin Endocrinol (Oxf). 1980 May;12(5):441-51. doi: 10.1111/j.1365-2265.1980.tb02734.x.
8
[Studies on influence of synthetic LH-RH and dbcAMP on normal chorionic villi and BeWo cells (author's transl)].合成促黄体生成素释放激素（LH-RH）和双丁酰环磷腺苷（dbcAMP）对正常绒毛膜绒毛和BeWo细胞影响的研究（作者译）
Nihon Sanka Fujinka Gakkai Zasshi. 1981 Dec;33(12):2105-14.
9
Actions of cyclic AMP, its butyryl derivatives and Na butyrate on the HCG output of malignant trophoblast cells in vitro.环磷酸腺苷、其丁酰衍生物及丁酸钠对体外恶性滋养层细胞人绒毛膜促性腺激素分泌量的作用
Br J Cancer. 1978 Jul;38(1):158-62. doi: 10.1038/bjc.1978.178.
10
Presence of immunoreactive luteinizing hormone-releasing factor in hydatidiform mole as compared with normal human trophoblastic tissue.
Placenta Suppl. 1981;3:257-61.

引用本文的文献

1
Spontaneous and gonadotropin-releasing hormone induced human chorionic gonadotropin release from superfused JAR choriocarcinoma cells.自发和促性腺激素释放激素诱导人绒毛膜促性腺激素从经超灌流的JAR绒毛膜癌细胞中释放。
Arch Gynecol Obstet. 1993;253(1):43-9. doi: 10.1007/BF02770633.
2
New aspects of placental endocrinology.胎盘内分泌学的新进展。
J Endocrinol Invest. 1990 Apr;13(4):353-71. doi: 10.1007/BF03349579.