Lee P F, Shihab Z, Eberle M
Lasers Surg Med. 1980;1(1):85-92. doi: 10.1002/lsm.1900010109.
partial ciliary processes argon laser photocoagulation (PCLP) in the management of glaucoma has been the subject of a carefully conducted, prospective 5+-year clinical trial in 22 eyes of 20 patients. The mean intraocular pressure (IOP) +/- SD was significantly lower (15.5 +/- 3.6 mm Hg) than before the procedure (29.9 +/- 10.1 mm Hg; 0.001 less than P less than 0.005, paired t-test). The mechanism of intraocular pressure reduction is due mainly to the reduction in the rate of aqueous humor formation with a mean outflow facility (C-value) +/- SD of 0.12 +/- 0.11 before and 0.12 +/- 0.06 microliter/min/mm Hg after the procedure. This new procedure, done on an out-patient basis, shows promise as a convenient, low-risk, and useful alternative procedure in selected glaucoma cases that are poorly controlled by medical or surgical measures. This new approach may also be used as an adjunct in the medical and/or surgical management of aphakic and ciliary block glaucoma.
部分睫状体氩激光光凝术（PCLP）用于青光眼治疗，是一项针对20例患者的22只眼睛精心开展的前瞻性5年以上临床试验的研究对象。平均眼压（IOP）±标准差显著低于手术前（分别为15.5±3.6 mmHg和29.9±10.1 mmHg；配对t检验，P＜0.001且P＜0.005）。眼压降低的机制主要是房水生成速率降低，术前平均房水流畅系数（C值）±标准差为0.12±0.11，术后为0.12±0.06微升/分钟/mmHg。这种新方法在门诊进行，对于药物或手术治疗控制不佳的特定青光眼病例，有望成为一种方便、低风险且有用的替代方法。这种新方法也可作为无晶状体和睫状环阻滞性青光眼药物和/或手术治疗的辅助手段。
