Delmonico F L, Cosimi A B, Russell P S
Ann Clin Res. 1981;13(4-5):373-81.
Survival of the extensively burned patient depends upon rapid excision of necrotic tissue, and skin grafting to obtain wound closure. When a sufficient supply of autogenous skin is not available to provide wound coverage, allograft skin has been successfully substituted. Although burn patients have been noted to be immunologically hyporesponsive, their immune response to skin allografts has necessitated the administration of immunosuppressive therapy, to assure the retention of the allografts until sufficient autogenous skin can be utilized. The temporary transplantation of skin allografts has proved successful in the treatment of extensively burned children.
大面积烧伤患者的存活取决于坏死组织的快速切除以及通过植皮实现伤口闭合。当无法获得足够的自体皮肤来覆盖伤口时，同种异体皮肤已成功用作替代物。尽管已注意到烧伤患者免疫反应低下，但他们对同种异体皮肤的免疫反应仍需要进行免疫抑制治疗，以确保同种异体皮肤在足够的自体皮肤可用之前得以保留。同种异体皮肤的临时移植已被证明在治疗大面积烧伤儿童方面是成功的。
