Hayek A
Endocr Res Commun. 1981;8(4):247-51. doi: 10.3109/07435808109045743.
While high concentrations of potassium directly stimulate pancreatic insulin release, it has not been shown whether potassium ions within the physiologic range produce the same effect. Rats fed a low potassium diet were given KCl intraperitoneally. Insulin levels measured in the portal vein were significantly elevated (172.9 +/- 17 vs 76.5 +/- 14.9 microunits/ml, p less than .05) at 30 minutes, compared to peripheral insulin levels in which the increase did not reach significance. Thus insulin, when measured in portal vein blood samples, is significantly released by potassium increments within the normal range in the absence of exogenous glucose loads.
虽然高浓度钾能直接刺激胰腺释放胰岛素，但尚未表明生理范围内的钾离子是否会产生同样的效果。给喂食低钾饮食的大鼠腹腔注射氯化钾。与外周胰岛素水平相比，门静脉中测得的胰岛素水平在30分钟时显著升高（172.9±17对76.5±14.9微单位/毫升，p<0.05），而外周胰岛素水平的升高未达到显著水平。因此，在没有外源性葡萄糖负荷的情况下，当在门静脉血样中测量时，正常范围内的钾增量会显著释放胰岛素。
