Foulon G, Adriambololona L, Nguyen B K, Durrande J B, Roux J, Martin-Bouyer G
Rev Epidemiol Sante Publique. 1981;29(4):389-98.
The incidence of clinical and infraclinical human brucellosis was estimated by survey undertaken in 1976 on a representative sample of the population of the Vaucluse (France) district. It is shown that, by combining research of late hypersensitivity and serologic tracking in 2084 individuals, the incidence of diagnosed clinical brucellosis, in the Vaucluse district is at least 3 to 5 times more important than the incidence evaluated by the official notifications, and that there are 10 times more infraclinical or non diagnosed brucellosis than diagnosed brucellosis. The results show the need of triple investigation by interview, serology and hypersensitivity test (complementarity of the three technics) so as to evaluate the true morbidity of this anthropozoonosis.
1976年对法国沃克吕兹地区有代表性的人群样本进行了调查,以此估算临床型和亚临床型人类布鲁氏菌病的发病率。结果表明,通过对2084人进行迟发型超敏反应研究和血清学追踪相结合的方法发现,沃克吕兹地区确诊的临床布鲁氏菌病发病率至少比官方通报的发病率高3至5倍,而且亚临床型或未确诊的布鲁氏菌病病例数量是确诊病例的10倍。结果表明,需要通过访谈、血清学和超敏反应试验进行三重调查(这三种技术相辅相成),以便评估这种人畜共患病的真实发病率。