Badzhinian S A
Biofizika. 1982 Mar-Apr;27(2):277-9.
Electrical conductivity of model membranes of lecithin, cardiolipin, gangliosides and lecithin-gangliosides mixture under the effect of PGE1, PGA1, PGI2 were investigated for a number of ions. Property of prostaglandins to increase membrane conductivity within a wide range of concentrations (10(-5) M--10(-10) M) was discovered. Cation selectivity of the membranes under the effect of prostaglandins was found. Ability of prostaglandins to change conformation of lipid membranes was indicated.
研究了在前列腺素E1、前列腺素A1、前列环素作用下,卵磷脂、心磷脂、神经节苷脂以及卵磷脂 - 神经节苷脂混合物的模型膜对多种离子的电导率。发现前列腺素在很宽的浓度范围(10^(-5) M - 10^(-10) M)内具有增加膜电导率的特性。还发现了前列腺素作用下膜的阳离子选择性。表明了前列腺素改变脂质膜构象的能力。