Wassef M, Le Charpentier Y, Monteil J P, Le Tien K, Galian A
Bull Cancer. 1982;69(1):11-21.
A case of undifferentiated carcinoma with lymphoid stroma of the paired gland is reported in a chinese woman with positive Epstein-Barr virus serology. The histologic appearance of the tumor is very similar to undifferentiated carcinomas nasopharyngeal type (UCNT). Ultrastructural study reveals features of epidermoid differentiation. Immunofluorescence study shows numerous and predominant IgA plasma cells in the stroma. The relationship between this tumor and the benign lymphoepithelial lesions of the salivary glands are discussed. The present case and the review of the literature emphasize the morphological and epidemiological similarities between UCNT and undifferentiated carcinoma with lymphoid stroma of the salivary glands.
报告了一例伴有淋巴间质的未分化癌,患者为一名中国女性,爱泼斯坦-巴尔病毒血清学检查呈阳性。肿瘤的组织学表现与鼻咽型未分化癌(UCNT)非常相似。超微结构研究显示有表皮样分化特征。免疫荧光研究显示间质中有大量且占优势的IgA浆细胞。讨论了该肿瘤与涎腺良性淋巴上皮病变之间的关系。本病例及文献复习强调了UCNT与涎腺伴有淋巴间质的未分化癌在形态学和流行病学上的相似性。