Debelle M, Carion J, Van der Mijnsbrugge J
Eur J Rheumatol Inflamm. 1981;4(1):103-6.
A comparison was made between indoprofen (800 mg/day), naproxen (500 mg/day) and placebo in 30 patients with well defined osteoarthritis of the hip. Treatments were given for 10 days each, according to a double-blind, cross-over design. Objective and subjective criteria were adopted for evaluation of effectiveness. Special attention was paid to side effects. There was a marked difference between the active drugs and placebo. Indoprofen was significantly better than naproxen on many variables, and was, in most cases, preferred to the latter, by patients and investigator.
对30例确诊为髋关节骨关节炎的患者，比较了吲哚美辛（800毫克/天）、萘普生（500毫克/天）与安慰剂的疗效。根据双盲交叉设计，每种治疗各给予10天。采用客观和主观标准评估疗效。特别关注了副作用。活性药物与安慰剂之间存在显著差异。在许多变量上，吲哚美辛显著优于萘普生，在大多数情况下，患者和研究者都更倾向于前者。
