终末期肾病患者的生存分析。

Analysis of survival of end-stage renal disease patients.

作者信息

Weller J M, Port F K, Swartz R D, Ferguson C W, Williams G W, Jacobs J F

出版信息

Kidney Int. 1982 Jan;21(1):78-83. doi: 10.1038/ki.1982.11.

DOI:10.1038/ki.1982.11

Abstract

Traditional life-table analysis of differences in patient survival for various end-stage renal disease (ESRD) treatment modalities ignore the fact the ESRD patients face sequential risks because they frequently experience more than one mode of therapy. A modification of the usual life-table analysis is suggested as being more appropriate. This modified method takes into account the "time-to-treatment" bias, which, in this instance, is the time spent on the first modality of treatment (that is, center dialysis). The survival data of more than 2,000 ESRD patients in the State of Michigan during the 5-year period, 1974 to 1978, are used to illustrate this method.

摘要

传统的生命表分析用于比较各种终末期肾病（ESRD）治疗方式下患者生存率的差异，但忽略了一个事实，即ESRD患者面临着相继的风险，因为他们经常接受不止一种治疗方式。有人建议对常规生命表分析进行修改，认为这种修改更合适。这种改进方法考虑了“治疗前时间”偏差，在这种情况下，“治疗前时间”是指在第一种治疗方式（即中心透析）上花费的时间。1974年至1978年这5年期间，密歇根州2000多名ESRD患者的生存数据用于说明这种方法。