Robertsson J A, Svenson S B, Renström L H
Res Vet Sci. 1982 Mar;32(2):225-30.
Intracutaneous injection of a crude supernatant fraction from homogenised Salmonella typhimurium (O antigens 4, 5, 12) or S dublin (O antigens 9, 12) in 250 cattle or calves from salmonella infected herds elicited in 27 per cent and 42 per cent, respectively, a local dermal reaction. Both the time course and histological examinations of biopsy materials indicated a delayed type of hypersensitivity reaction. No local dermal reactions were seen in any of 250 heads of cattle or calves from control herds. The immunological characterisation of the S typhimurium and S dublin crude extracts revealed that they contained O antigens (ie, lipopolysaccharides) and outer membrane proteins, porins. A Yersinia enterocolitica serotype O3 extract did not evoke skin reactions in any of 70 tested animals. Fifteen calves infected with S typhimurium and five with S dublin exhibited increased ELISA titres against the O antigenically homologous lipopolysaccharides.
对来自感染沙门氏菌牛群的250头牛或犊牛皮内注射鼠伤寒沙门氏菌（O抗原4、5、12）或都柏林沙门氏菌（O抗原9、12）匀浆后的粗上清液组分，分别有27%和42%出现了局部皮肤反应。活检材料的时间进程和组织学检查均表明是迟发型超敏反应。来自对照牛群的250头牛或犊牛均未出现局部皮肤反应。对鼠伤寒沙门氏菌和都柏林沙门氏菌粗提物的免疫学特性分析表明，它们含有O抗原（即脂多糖）和外膜蛋白、孔蛋白。小肠结肠炎耶尔森氏菌O3血清型提取物在70只受试动物中均未引起皮肤反应。15头感染鼠伤寒沙门氏菌的犊牛和5头感染都柏林沙门氏菌的犊牛针对O抗原同源脂多糖的ELISA效价升高。
