Nisbet N W
Scand J Immunol. 1981 Dec;14(6):599-605. doi: 10.1111/j.1365-3083.1981.tb00601.x.
The absorption of bone in Grüneberg microphthalmic mice and the op op osteopetrotic rat can be stimulated by an injection of compatible bone marrow, and complete resorption can occur. It is probable that the bone-absorbing osteoclast responsible is derived from a haematopoietic stem cell resident in the bone marrow (BM). Maintenance of the resorption depends on the survival of donor cells which has an important implication for clinical therapy in man. No evidence was found that the thymus played a leading role in the mechanism of bone absorption in the Grüneberg microphthalmic mouse, or in the op op rat.
在格林伯格小眼小鼠和op op骨石化大鼠中，注射相容的骨髓可刺激骨吸收，并且可能发生完全吸收。负责骨吸收的破骨细胞很可能源自驻留在骨髓（BM）中的造血干细胞。吸收的维持取决于供体细胞的存活，这对人类临床治疗具有重要意义。未发现有证据表明胸腺在格林伯格小眼小鼠或op op大鼠的骨吸收机制中起主导作用。
