脂肪细胞受体的亲和力变化未能改变胰岛素刺激的葡萄糖转运。
Affinity change of the adipocyte receptor fails to alter insulin-stimulated glucose transport.
作者信息
McCaleb M L, Donner D B
出版信息
Biochem J. 1982 Jan 15;202(1):263-5. doi: 10.1042/bj2020263.
Abstract
Occupancy increased the affinity of the insulin receptor of the adipocyte. During the affinity change the half-maximal sensitivity of glucose transport to insulin stimulation was unaltered. Decreased maximum response of transport only occurred after the affinity change. There was not a simple relationship between receptor affinity and insulin stimulation of glucose transport in the adipocyte.
摘要
占据增加了脂肪细胞胰岛素受体的亲和力。在亲和力变化期间，葡萄糖转运对胰岛素刺激的半最大敏感性未改变。只有在亲和力变化之后才出现转运的最大反应降低。在脂肪细胞中，受体亲和力与胰岛素刺激的葡萄糖转运之间不存在简单的关系。
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