Mäkäräinen L, Ylikorkala O
Br J Obstet Gynaecol. 1982 May;89(5):402-7. doi: 10.1111/j.1471-0528.1982.tb05084.x.
To study the effect of prostacyclin (PGI2) on the contractility of the non-pregnant human uterus, the intrauterine pressures in the isthmus and fundus of the uterus were recorded before, during and after intravenous PGI2 at different phases of two consecutive menstrual cycles in eight women. Infusions of 1-8 ng of PGI2 min-1 kg-1 for 20 min caused no changes in intrauterine pressure either during menstruation or any other phase of the cycle when compared with the contractility patterns in the same woman during the control infusion. Thus these data suggest that circulating PGI2 is not involved in regulating the contractility of the non-pregnant human myometrium.
为研究前列环素（PGI2）对未孕人体子宫收缩性的影响，在8名女性连续两个月经周期的不同阶段，记录静脉注射PGI2之前、期间和之后子宫峡部和底部的宫内压力。与同一女性在对照输注期间的收缩模式相比，以1 - 8 ng·min-1·kg-1的剂量输注PGI2 20分钟，在月经期间或周期的任何其他阶段均未引起宫内压力变化。因此，这些数据表明循环中的PGI2不参与调节未孕人体子宫肌层的收缩性。
