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关于特应性皮炎患者未受累皮肤及健康对照者皮肤常驻需氧菌菌群的研究。

On the resident aerobic bacterial skin flora in unaffected skin of patients with atopic dermatitis and in healthy controls.

作者信息

Gloor M, Peters G, Stoika D

出版信息

Dermatologica. 1982 Apr;164(4):258-65. doi: 10.1159/000250099.

Abstract

In 14 patients with atopic dermatitis the superficial bacteria from unaffected skin were extracted with the scrub method, aerobically cultured, and analysis qualitatively and quantitatively. For comparison, 12 healthy subjects served as control group. Staphylococcus aureus, as well as coagulase-negative staphylococci were significantly increased in patients with atopic dermatitis. It is assumed that special characteristics of the horny layer in atopic dermatitis favor the growth of aerobic bacteria. The qualitative biotyping and phage typing gave no support to the claim that special bacteria dominate the microbial flora of the skin of patients with atopic dermatitis.

摘要

对14例特应性皮炎患者,采用擦洗法提取未受累皮肤的表层细菌,进行需氧培养,并进行定性和定量分析。作为对照,选取12名健康受试者作为对照组。特应性皮炎患者的金黄色葡萄球菌以及凝固酶阴性葡萄球菌显著增多。据推测,特应性皮炎角质层的特殊特性有利于需氧菌生长。定性生物分型和噬菌体分型并不支持存在特殊细菌主导特应性皮炎患者皮肤微生物群这一说法。

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