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丙吡胺与普鲁卡因胺治疗强直性肌营养不良症中肌强直的对比研究。

A comparative study of disopyramide and procainamide in the treatment of myotonia in myotonic dystrophy.

作者信息

Finlay M

出版信息

J Neurol Neurosurg Psychiatry. 1982 May;45(5):461-3. doi: 10.1136/jnnp.45.5.461.

DOI:10.1136/jnnp.45.5.461
PMID:7045292
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1083128/
Abstract

Ten patients with myotonic dystrophy were allocated at random to treatment with disopyramide and procainamide in a cross-over trial. Disopyramide was found to be at least as effective as procainamide in the relief of myotonia; and two patients who could not tolerate procainamide both tolerated disopyramide.

摘要

十名强直性肌营养不良患者被随机分配，在交叉试验中接受丙吡胺和普鲁卡因胺治疗。结果发现，丙吡胺在缓解肌强直方面至少与普鲁卡因胺一样有效；两名不能耐受普鲁卡因胺的患者都能耐受丙吡胺。

相似文献

1
A comparative study of disopyramide and procainamide in the treatment of myotonia in myotonic dystrophy.丙吡胺与普鲁卡因胺治疗强直性肌营养不良症中肌强直的对比研究。
J Neurol Neurosurg Psychiatry. 1982 May;45(5):461-3. doi: 10.1136/jnnp.45.5.461.
2
[Comparative study of the acute and chronic effect of disopyramide and procainamide in ventricular extrasystole over a long time].
Ann Cardiol Angeiol (Paris). 1982 Jul-Sep;31(5):395-9.
3
A double-blind trial of disopyramide, procaineamide and digoxin in paroxysmal suptraventricular tachycardia.双嘧达莫、普鲁卡因胺和地高辛治疗阵发性室上性心动过速的双盲试验。 （注：原文中的“disopyramide”有误，应该是“dipyridamole”，翻译为双嘧达莫 ；“suptraventricular”有误，应该是“supraventricular”，翻译为室上性 ） 正确译文：双嘧达莫、普鲁卡因胺和地高辛治疗阵发性室上性心动过速的双盲试验。 （按照正确的英文重新翻译一遍：A double-blind trial of dipyridamole, procainamide and digoxin in paroxysmal supraventricular tachycardia.）
Clin Cardiol. 1979 Jun;2(3):179-84. doi: 10.1002/clc.4960020302.
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[Computerized analysis of the clinical effectiveness of intravenous/disopyramide and procainamide in patients with stabilized and complicated ventricular extrasystole].[静脉注射双异丙吡胺和普鲁卡因酰胺对稳定型和复杂型室性早搏患者临床疗效的计算机分析]
Boll Soc Ital Cardiol. 1979;24(12):1297-305.
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[Encopresis revealing myotonic dystrophy in 2 children].
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[Neurophysiological studies on the temporary paresis in myotonia congenita and dystrophia myotonica].[先天性肌强直和强直性肌营养不良症中暂时性麻痹的神经生理学研究]
Z Neurol. 1973 Apr 2;204(2):135-48.

引用本文的文献

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2
Effectiveness and safety of mexiletine versus placebo in patients with myotonia: a systematic review and meta-analysis.美西律对比安慰剂治疗肌强直患者的有效性和安全性：系统评价和荟萃分析。
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3
Unreviewed reports.未经审核的报告。
Br Med J (Clin Res Ed). 1985 Apr 6;290(6474):1042.
4
Drug treatment for myotonia.肌强直的药物治疗。
Cochrane Database Syst Rev. 2006 Jan 25;2006(1):CD004762. doi: 10.1002/14651858.CD004762.pub2.
5
Disopyramide. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in cardiac arrhythmias.丙吡胺。对其药效学和药代动力学特性以及在心律失常治疗中的应用的重新评估。
Drugs. 1987 Aug;34(2):151-87. doi: 10.2165/00003495-198734020-00001.

本文引用的文献

1
Procaine amide in the treatment of myotonia.普鲁卡因胺治疗肌强直。
Brain. 1955;78(1):81-91. doi: 10.1093/brain/78.1.81.
2
The treatment of myotonia: a controlled clinical trial.肌强直的治疗：一项对照临床试验。
Brain. 1959 Mar;82(1):81-91. doi: 10.1093/brain/82.1.81.
3
Electrophysiological study of dystrophia myotonica.强直性肌营养不良的电生理研究
J Neurol Neurosurg Psychiatry. 1971 Apr;34(2):132-9.
4
Therapy of myotonia. A double-blind evaluation of diphenylhydantoin, procainamide, and placebo.肌强直的治疗。苯妥英、普鲁卡因胺和安慰剂的双盲评估。
Neurology. 1967 Apr;17(4):359-67. doi: 10.1212/wnl.17.4.359.
5
Incidence, severity, and time-course of motoneurone dysfunction in myotonic dystrophy: their significance for an understanding of anticipation.强直性肌营养不良中运动神经元功能障碍的发病率、严重程度及病程：它们对理解遗传早现的意义。
J Neurol Neurosurg Psychiatry. 1978 Oct;41(10):882-93. doi: 10.1136/jnnp.41.10.882.
6
Disopyramide phosphate: is it just another quinidine.
Can J Physiol Pharmacol. 1978 Apr;56(2):326-31. doi: 10.1139/y78-049.