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糖尿病儿童的糖化血红蛋白(HbA1)总水平。

Total glycosylated haemoglobin (HbA1) levels in diabetic children.

作者信息

Mann N P, Johnston D I

出版信息

Arch Dis Child. 1982 Jun;57(6):434-7. doi: 10.1136/adc.57.6.434.

Abstract

Total glycosylated haemoglobin (HbA1) levels from capillary blood were studied retrospectively during a 1-year period in 148 diabetic children aged between 1.9 and 16.8 years. The clinic range for HbA1 was 6.7 to 22.2% and the results were normally distributed (mean +/- SD 13.2 +/- 2.8%). The normal range in non-diabetics using this method is 4.9 to 8.0%. Results from children who had had diabetes for more than 5 years were higher than those from children with diabetes of 2 to 5 years' duration. Girls had higher average values during the 1-year period than boys. HbA1 measurement serves to identify the deficiencies of current diabetic treatment regimens. It also has more immediate practical benefits in focusing attention on children whose control is deteriorating.

摘要

回顾性研究了148名年龄在1.9至16.8岁之间的糖尿病儿童在1年期间毛细血管血中的总糖化血红蛋白(HbA1)水平。HbA1的临床范围为6.7%至22.2%,结果呈正态分布(均值±标准差为13.2±2.8%)。使用该方法的非糖尿病患者的正常范围是4.9%至8.0%。患糖尿病超过5年的儿童的结果高于患糖尿病2至5年的儿童。在这1年期间,女孩的平均值高于男孩。HbA1测量有助于识别当前糖尿病治疗方案的不足之处。它在关注病情恶化的儿童方面也有更直接的实际益处。

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本文引用的文献

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The problem of "cheating" in the diabetic child and adolescent.
Diabetes Care. 1981 Jan-Feb;4(1):116-20. doi: 10.2337/diacare.4.1.116.
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Diabetes in adolescence.青少年糖尿病
Diabetologia. 1981 May;20(5):517-23. doi: 10.1007/BF00252758.
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Lancet. 1980 Aug 9;2(8189):279-82. doi: 10.1016/s0140-6736(80)90233-0.
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Iron deficiency and glycosylated haemoglobin A.
Lancet. 1980 Jul 19;2(8186):141. doi: 10.1016/s0140-6736(80)90019-7.
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Editorial: "Control" and diabetes.社论:“控制”与糖尿病
N Engl J Med. 1976 Apr 29;294(18):1004-5. doi: 10.1056/NEJM197604292941811.

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