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对高纯度猪胰岛素的过敏反应。通过放射性变应原吸附试验（RAST）及RAST抑制试验加以证实。

An anaphylactic reaction to highly purified pork insulin. Confirmation by RAST and RAST inhibition.

作者信息

Carini C, Brostoff J, Kurtz A B

出版信息

Diabetologia. 1982 May;22(5):324-6. doi: 10.1007/BF00253575.

DOI:10.1007/BF00253575
PMID:7047280
Abstract

We describe a patient who had an anaphylactic reaction to highly purified pork insulin; he was not allergic however to beef insulin. The sensitivity to pork but not to beef insulin was confirmed by skin testing, radioallergosorbent test (RAST) and RAST inhibition. A scheme is suggested for the investigation of such patients.

摘要

我们描述了一名对高纯度猪胰岛素发生过敏反应的患者；然而，他对牛胰岛素不过敏。通过皮肤试验、放射变应原吸附试验（RAST）和RAST抑制试验证实了其对猪胰岛素而非牛胰岛素敏感。本文提出了针对此类患者的调查方案。

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本文引用的文献

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Preparation of iodine-131 labelled human growth hormone of high specific activity.高比活度碘-131标记人生长激素的制备
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2
Immediate-type allergy against insulin itself: clinical and immunologic studies on a diabetic patient with insulin intolerance.对胰岛素本身的速发型过敏反应：对一名胰岛素不耐受糖尿病患者的临床和免疫学研究
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Generalised allergy to porcine and bovine monocomponent insulins.对猪和牛单组分胰岛素的全身性过敏。
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4
Serological analysis of human IgG and IgE anti-insulin antibodies by solid-phase radioimmunoassays.通过固相放射免疫测定法对人IgG和IgE抗胰岛素抗体进行血清学分析。
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Circulating insulin-binding antibodies.循环胰岛素结合抗体。
Diabetologia. 1980 Oct;19(4):329-34. doi: 10.1007/BF00280515.
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Generalised allergy to porcine and bovine monocomponent insulins.
Br Med J. 1980 Aug 2;281(6236):355-6. doi: 10.1136/bmj.281.6236.355.
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Diagnosis of allergy by an in-vitro test for allergen antibodies.通过过敏原抗体体外检测诊断过敏。
Lancet. 1967 Nov 25;2(7526):1105-7. doi: 10.1016/s0140-6736(67)90615-0.
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Chronic urticaria from isophane insulin therapy; sensitivity associated with noninsulin components in commercial preparations.
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Generalised allergic reaction to monocomponent insulin.对单组分胰岛素的全身性过敏反应。
Br Med J. 1977 Sep 17;2(6089):736-7. doi: 10.1136/bmj.2.6089.736.
10
Anti-insulin IgE in diabetics.糖尿病患者体内的抗胰岛素IgE
J Clin Endocrinol Metab. 1977 Dec;45(6):1159-64. doi: 10.1210/jcem-45-6-1159.