Wüthrich B, Kägi M K, Stücker W
Department of Dermatology, University Hospital, Zurich, Switzerland.
Allergy. 1997 Nov;52(11):1133-7. doi: 10.1111/j.1398-9995.1997.tb00189.x.
We report five cases of anaphylactic reaction to carmine (cochineal, E120) after patients drank an alcoholic beverage. By means of positive skin prick tests (SPT) and positive RAST to carmine. IgE-mediated sensitization could be established. One nonatopic patient showed also a great amount of serum IgE antibodies to the carmine acid-albumin conjugate. Due to its widespread use in the food and cosmetic industry, carmine should be tested in the allergy work-up in case of allergic reactions after a drink or a meal.
我们报告了5例患者在饮用酒精饮料后对胭脂红（胭脂虫红，E120）发生过敏反应的病例。通过对胭脂红进行阳性皮肤点刺试验（SPT）和阳性放射性变应原吸附试验（RAST），可确定为IgE介导的致敏。1例非特应性患者对胭脂红酸 - 白蛋白结合物也显示出大量血清IgE抗体。由于胭脂红在食品和化妆品工业中广泛使用，因此在饮用或进食后发生过敏反应时，应在过敏检查中对胭脂红进行检测。
