Dolgov V V, Zaikina O E, Bondarenko M F, Repin V S
Diabetologia. 1982 May;22(5):338-43. doi: 10.1007/BF00253578.
Scanning electron microscope studies of the aorta and other major arteries have been performed in alloxan-induced diabetic rabbits. After 5 weeks, a variety of structural abnormalities of the endothelial lining were detected including a significant increase in the number of argyrophilic cells and an increased number of craters or openings in the endothelial junctional region. Evidence of more extensive micro-damage was present after 5 months duration of diabetes. These zones with structural changes in the endothelial lining of major vessels seem to be areas of high predilection to atherosclerosis in diabetes.
已对四氧嘧啶诱导的糖尿病兔的主动脉和其他主要动脉进行了扫描电子显微镜研究。5周后，检测到内皮衬里的多种结构异常，包括嗜银细胞数量显著增加以及内皮连接区域的坑洼或开口数量增加。糖尿病持续5个月后，出现了更广泛的微损伤证据。主要血管内皮衬里发生结构变化的这些区域似乎是糖尿病中动脉粥样硬化的高发部位。
