Feldman E C, Nelson R W
J Am Vet Med Assoc. 1982 Jun 15;180(12):1432-7.
Insulin-induced hyperglycemia was diagnosed in 8 dogs with diabetes mellitus. Owners sought veterinary care because of polydipsia, polyuria, polyphagia, persistent morning glycosuria, or seizures in their dogs. These abnormalities had persisted despite increasing the dosage of insulin. Insulin-induced posthypoglycemic hyperglycemia was diagnosed by determining blood glucose concentrations every 2 hours during a 24-hour period, beginning at 8 A.M. Wide fluctuations in the blood glucose concentration were reduced by decreasing the daily insulin dose. The signs observed by the owners disappeared after the insulin dose was reduced.
8只患有糖尿病的犬被诊断出胰岛素诱导的高血糖症。由于犬出现烦渴、多尿、多食、持续性晨起糖尿或癫痫发作，其主人寻求兽医护理。尽管增加了胰岛素剂量，这些异常情况仍持续存在。通过从上午8点开始在24小时内每2小时测定一次血糖浓度，诊断出胰岛素诱导的低血糖后高血糖症。通过减少每日胰岛素剂量，血糖浓度的大幅波动得以降低。在减少胰岛素剂量后，主人观察到的症状消失了。
