Burns R B
Res Vet Sci. 1982 May;32(3):359-67.
Peyer's patches (PP) were identified in the small intestine of the domestic fowl by their thickened villi, flattened epithelium which lacked goblet cells and by the accumulations of lymphocytes in the form of encapsulated germinal centres (GC) and diffuse lymphoid tissue (DLT). Particles of orally administered carbon were seen in GC and DLT, in macrophages and within epithelial cells (M cells). Faults in the PP epithelium, which was positive for alkaline phosphatase, allowed the extrusion of lymphocytes into the intestinal lumen. Immunofluorescence detected more lymphoid cells with cytoplasmic IgG than IgA or IgM. Specific antibody production was seen in cells of GC ad DLT in PP from fowls that had received multiple injections of horse serum.
通过增厚的绒毛、缺乏杯状细胞的扁平上皮以及以包囊生发中心（GC）和弥散淋巴组织（DLT）形式存在的淋巴细胞聚集，在家禽小肠中识别出派尔集合淋巴结（PP）。口服碳颗粒可见于GC和DLT、巨噬细胞以及上皮细胞（M细胞）内。碱性磷酸酶呈阳性的PP上皮存在缺陷，使得淋巴细胞能够排入肠腔。免疫荧光检测发现，胞质内含有IgG的淋巴细胞比含有IgA或IgM的更多。在多次注射马血清的家禽的PP中，GC和DLT的细胞可见特异性抗体产生。
