Shivaramaiah Chaitanya, Barta John R, Hernandez-Velasco Xochitl, Téllez Guillermo, Hargis Billy M
Department of Poultry Science, University of Arkansas, Fayetteville, AR, USA.
Department of Pathobiology, University of Guelph, ON, Canada.
Vet Med (Auckl). 2014 Apr 28;5:23-34. doi: 10.2147/VMRR.S57839. eCollection 2014.
Coccidiosis, caused by parasites of the genus , is probably the most expensive parasitic disease of poultry. Species of are ubiquitous where poultry are raised and are known to cause drastic reductions in performance and induce mortality, thereby affecting the overall health status of poultry. Chemotherapy has been the predominant form of disease control for many years, even though vaccination is steadily gaining importance as a feasible control method. The objective of this review is to highlight recent advancements in understanding the role of host immunity against coccidiosis. In addition, pros and cons associated with chemotherapy and the role of vaccination as an increasingly popular disease control method are discussed. Finally, the role played by recombinant vaccines as a potential vaccination tool is highlighted. With interest growing rapidly in understanding host-parasite biology, recent developments in designing recombinant vaccines and potential epitopes that have shown promise are mentioned.
球虫病由艾美耳属寄生虫引起，可能是家禽最昂贵的寄生虫病。艾美耳属物种在家禽饲养场所普遍存在，已知会导致家禽生产性能急剧下降并引发死亡，从而影响家禽的整体健康状况。尽管疫苗接种作为一种可行的控制方法正日益重要，但多年来化疗一直是疾病控制的主要形式。本综述的目的是强调在理解宿主免疫对球虫病的作用方面的最新进展。此外，还讨论了化疗的利弊以及疫苗接种作为一种越来越受欢迎的疾病控制方法的作用。最后，强调了重组疫苗作为一种潜在疫苗接种工具所起的作用。随着对宿主 - 寄生虫生物学的理解兴趣迅速增长，还提到了设计重组疫苗和已显示出前景的潜在表位方面的最新进展。
