Massey J A, Abrams P
Br J Urol. 1986 Apr;58(2):125-8. doi: 10.1111/j.1464-410x.1986.tb09010.x.
Seventy-two women with proven detrusor instability completed a novel clinical trial of the new anticholinergic emepronium carrageenate (Cetiprin novum), which allowed for dose titration. The tolerated dose has been shown to correlate with the severity of symptoms. Statistically significant improvement was achieved in symptomatic and urodynamic parameters without serious side effects.
72名确诊为逼尿肌不稳定的女性完成了一项关于新型抗胆碱能药物角叉菜酸乙胺戊酯(新西替普林)的新型临床试验,该试验允许进行剂量滴定。已证明耐受剂量与症状严重程度相关。在症状和尿动力学参数方面取得了具有统计学意义的改善,且无严重副作用。