隐球菌性脑膜炎的假性暴发

Pseudooutbreak of cryptococcal meningitis.

作者信息

Hopfer R L, Katz R L, Fainstein V

出版信息

J Clin Microbiol. 1982 Jun;15(6):1141-3. doi: 10.1128/jcm.15.6.1141-1143.1982.

DOI:10.1128/jcm.15.6.1141-1143.1982

PMID:7050150

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC272266/

Abstract

A pseudooutbreak of cryptococcal meningitis was caused by the use of contaminated albumin solution used in the preparation of Papanicolaou-stained slides of cerebrospinal fluid. Organisms were seen in cytocentrifuge preparations, but not in India ink preparations of cerebrospinal fluid specimens. Cryptococcal antigen tests were positive and Cryptococcus neoformans was cultured from the albumin-treated cerebrospinal fluid specimens and from the albumin solution.

摘要

一起隐球菌性脑膜炎的假性暴发是由用于制备脑脊液巴氏染色玻片的白蛋白溶液被污染所致。在细胞离心涂片上可见菌体，但在脑脊液标本的墨汁涂片上未见。隐球菌抗原检测呈阳性，从经白蛋白处理的脑脊液标本和白蛋白溶液中培养出了新型隐球菌。